Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50002966
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.680nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1(Thr37/46) peptide as substrate measured after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 1nMAssay Description:Inhibition of human PI3K p120gamma using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465281(CHEMBL4284400)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1(Thr37/46) peptide as substrate measured after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 12nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PI3K p110delta/p85alpha using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465281(CHEMBL4284400)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465281(CHEMBL4284400)
Affinity DataIC50: 19nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1(Thr37/46) peptide as substrate measured after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465292(CHEMBL4279898)
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465289(CHEMBL4276933)
Affinity DataIC50: 28nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465282(CHEMBL4280265)
Affinity DataIC50: 33nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 34nMAssay Description:Inhibition of human PI3K p110beta/p85alpha using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465288(CHEMBL4294409)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465277(CHEMBL4294612)
Affinity DataIC50: 45nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465286(CHEMBL4291635)
Affinity DataIC50: 49nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465290(CHEMBL4280614)
Affinity DataIC50: 49nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465291(CHEMBL4277571)
Affinity DataIC50: 54nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465285(CHEMBL4280989)
Affinity DataIC50: 57nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465279(CHEMBL4288222)
Affinity DataIC50: 64nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465281(CHEMBL4284400)
Affinity DataIC50: 66nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465279(CHEMBL4288222)
Affinity DataIC50: 67nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465287(CHEMBL4295052)
Affinity DataIC50: 77nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465287(CHEMBL4295052)
Affinity DataIC50: 78nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465284(CHEMBL4288517)
Affinity DataIC50: 81nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465278(CHEMBL4288258)
Affinity DataIC50: 89nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465283(CHEMBL4281223)
Affinity DataIC50: 99nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465284(CHEMBL4288517)
Affinity DataIC50: 106nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465277(CHEMBL4294612)
Affinity DataIC50: 109nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465289(CHEMBL4276933)
Affinity DataIC50: 119nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465291(CHEMBL4277571)
Affinity DataIC50: 138nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465280(CHEMBL4287809)
Affinity DataIC50: 141nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465292(CHEMBL4279898)
Affinity DataIC50: 153nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465286(CHEMBL4291635)
Affinity DataIC50: 163nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465283(CHEMBL4281223)
Affinity DataIC50: 198nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465290(CHEMBL4280614)
Affinity DataIC50: 223nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465285(CHEMBL4280989)
Affinity DataIC50: 246nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465288(CHEMBL4294409)
Affinity DataIC50: 400nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465282(CHEMBL4280265)
Affinity DataIC50: 400nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465280(CHEMBL4287809)
Affinity DataIC50: 400nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed