Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50001146
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataKd:  620nMAssay Description:Binding affinity to human N-terminal 6His-tagged HSP90alpha (1 to 236 residues) expressed in Escherichia coli BL21star/Rosetta2 (DE3) at 298 K by ITC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270471(CHEMBL4075556)
Affinity DataKd:  320nMAssay Description:Binding affinity to human N-terminal 6His-tagged HSP90alpha (1 to 236 residues) expressed in Escherichia coli BL21star/Rosetta2 (DE3) at 298 K by ITC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetEndoplasmin(Dog)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetEndoplasmin(Dog)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270471(CHEMBL4075556)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270471(CHEMBL4075556)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataIC50: 1.32E+4nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmin(Dog)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270472(CHEMBL4098757)
Affinity DataIC50: 1.74E+4nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270472(CHEMBL4098757)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmin(Dog)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270471(CHEMBL4075556)
Affinity DataKi:  440nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetEndoplasmin(Dog)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataKi:  440nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270471(CHEMBL4075556)
Affinity DataKi:  840nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50087812(CHEMBL3426787)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmin(Dog)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270472(CHEMBL4098757)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of FITC-geldanamycin from full length dog GRP94 at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Hauptman-Woodward Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50270472(CHEMBL4098757)
Affinity DataKi: >1.30E+4nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)