Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50002226
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM34233(EBSELEN | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...)
Affinity DataIC50: 400nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50455375(CHEMBL4208308)
Affinity DataIC50: 450nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50455377(E927a | NSC-674447)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028969(CHEMBL3122204)
Affinity DataIC50: 550nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM43362(TETRAMETHYLTHIURAM DISULFIDE | SMR000059023 | MLS0...)
Affinity DataIC50: 550nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 600nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM60840(2-(2-pyridinyldisulfanyl)pyridine | SMR000473199 |...)
Affinity DataIC50: 650nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM34233(EBSELEN | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...)
Affinity DataIC50: 730nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028971(CHEMBL3335713)
Affinity DataIC50: 790nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028969(CHEMBL3122204)
Affinity DataIC50: 860nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50455375(CHEMBL4208308)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM43362(TETRAMETHYLTHIURAM DISULFIDE | SMR000059023 | MLS0...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028968(CHEMBL3335712)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028971(CHEMBL3335713)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50455377(E927a | NSC-674447)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM24776(1,4-dihydronaphthalene-1,4-dione | 1,4-Naphthoquin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM60840(2-(2-pyridinyldisulfanyl)pyridine | SMR000473199 |...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028972(Benzene Selenoic Acid)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50028972(Benzene Selenoic Acid)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50010231(CHEMBL107217 | sodium diethyldithiocarbamate | sod...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM24776(1,4-dihydronaphthalene-1,4-dione | 1,4-Naphthoquin...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50455376(CYSTAMINE DIHYDROCHLORIDE)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50324901(2,2-dihydroxy-1H-indene-1,3(2H)-dione | CHEMBL1221...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50010231(CHEMBL107217 | sodium diethyldithiocarbamate | sod...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50324901(2,2-dihydroxy-1H-indene-1,3(2H)-dione | CHEMBL1221...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50130701(sodium selenate(VI) | lambda~4~-selenium oxide; di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50422268(GLUTATHIONE | GSH)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM225231(OXIGLUTATIONE | Disulfide, Glutathione | Oxidized ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50094892(9,10-anthraquinone | 9,10-quinone | Az-Q | anthrad...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50130701(sodium selenate(VI) | lambda~4~-selenium oxide; di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50455376(CYSTAMINE DIHYDROCHLORIDE)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM7968(2-aminoethane-1-thiol | Cysteamine | US20250145565...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50422268(GLUTATHIONE | GSH)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM225231(OXIGLUTATIONE | Disulfide, Glutathione | Oxidized ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM50094892(9,10-anthraquinone | 9,10-quinone | Az-Q | anthrad...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Radboud University

Curated by ChEMBL
LigandPNGBDBM7968(2-aminoethane-1-thiol | Cysteamine | US20250145565...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed