Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50002613
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460520(CHEMBL4228293)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460521(CHEMBL4228332)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460518(CHEMBL4228977)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460523(CHEMBL4225627)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460524(CHEMBL4225893)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460518(CHEMBL4228977)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460522(CHEMBL4226829)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460521(CHEMBL4228332)
Affinity DataIC50: 730nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460523(CHEMBL4225627)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460520(CHEMBL4228293)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460517(CHEMBL4227185)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460524(CHEMBL4225893)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460522(CHEMBL4226829)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460517(CHEMBL4227185)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant mouse HDAC6 expressed in HEK293T cells co-expressing mouse HDA2 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 expressed in HEK293T cells using Ac-KGLGK(Ac)-MCA as substrate after 30 mins in presence of DTT by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50268183(CHEMBL4080410)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460525(CHEMBL4228731)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50460519(CHEMBL4226061)
Affinity DataIC50: 5.53E+4nMAssay Description:Inhibition of human placenta topoisomerase 2alpha assessed as reduction in pBR322 supercoiled DNA relaxation after 30 mins by ethidium bromide staini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed