Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50006767
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503191(CHEMBL4587631)
Affinity DataEC50:  6nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503179(CHEMBL4556144)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503172(CHEMBL4473537)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503192(CHEMBL4570470)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503174(CHEMBL4470447)
Affinity DataEC50:  15nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503206(CHEMBL4586335)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503176(CHEMBL4448031)
Affinity DataEC50:  18nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503162(CHEMBL4580527)
Affinity DataEC50:  18nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503194(CHEMBL4473685)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503177(CHEMBL4465783)
Affinity DataEC50:  23nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503190(CHEMBL4442487)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503166(CHEMBL4576215)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503167(CHEMBL4456816)
Affinity DataEC50:  29nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503159(CHEMBL4580916)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503171(CHEMBL4467158)
Affinity DataEC50:  33nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503198(CHEMBL4568356)
Affinity DataEC50:  37nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503184(CHEMBL4437986)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503164(CHEMBL4483344)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503160(CHEMBL4564190)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503181(CHEMBL4588508)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503204(CHEMBL4546388)
Affinity DataEC50:  64nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503170(CHEMBL4569581)
Affinity DataEC50:  68nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503169(CHEMBL4534604)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503196(CHEMBL4580525)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503205(CHEMBL4590535)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503188(CHEMBL4538026)
Affinity DataEC50:  71nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503189(CHEMBL4447550)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503173(CHEMBL4583006)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503199(CHEMBL4545027)
Affinity DataEC50:  86nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503202(CHEMBL4446625)
Affinity DataEC50:  90nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503203(CHEMBL4453680)
Affinity DataEC50:  118nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503180(CHEMBL4525401)
Affinity DataEC50:  140nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503183(CHEMBL4546739)
Affinity DataEC50:  140nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503161(CHEMBL4447702)
Affinity DataEC50:  141nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503163(CHEMBL4460927)
Affinity DataEC50:  148nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503165(CHEMBL4464043)
Affinity DataEC50:  155nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503193(CHEMBL4460043)
Affinity DataEC50:  180nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503175(CHEMBL4525207)
Affinity DataEC50:  190nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503178(CHEMBL4514174)
Affinity DataEC50:  210nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503182(CHEMBL4436220)
Affinity DataEC50:  270nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503200(CHEMBL4455228)
Affinity DataEC50:  290nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503197(CHEMBL4557213)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503168(CHEMBL4451873)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503187(CHEMBL4563304)
Affinity DataEC50:  620nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503185(CHEMBL4471540)
Affinity DataEC50:  730nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503186(CHEMBL4439927)
Affinity DataEC50:  1.07E+3nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503201(CHEMBL4564533)
Affinity DataEC50:  2.24E+3nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50234596(CHEMBL1884989)
Affinity DataEC50:  3.00E+3nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503195(CHEMBL4459398)
Affinity DataEC50: >5.00E+3nMAssay Description:Positive allosteric modulation of human mGluR2 expressed in human Chem1 cells assessed as increase in glutamate-induced intracellular calcium influx ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50503164(CHEMBL4483344)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
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