Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50002606
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460420BDBM50460420(CHEMBL4228565)
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460430BDBM50460430(CHEMBL4228304)
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460429BDBM50460429(CHEMBL4229142)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460414BDBM50460414(CHEMBL4227898)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460416BDBM50460416(CHEMBL4225063)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460429BDBM50460429(CHEMBL4229142)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460429BDBM50460429(CHEMBL4229142)
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460422BDBM50460422(CHEMBL4228336)
Affinity DataIC50: 22nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460424BDBM50460424(CHEMBL4226968)
Affinity DataIC50: 22nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460432BDBM50460432(CHEMBL4225611)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460416BDBM50460416(CHEMBL4225063)
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460419BDBM50460419(CHEMBL4224796)
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460421BDBM50460421(CHEMBL4227702)
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460423BDBM50460423(CHEMBL4227225)
Affinity DataIC50: 37nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460431BDBM50460431(CHEMBL4226914)
Affinity DataIC50: 37nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460420BDBM50460420(CHEMBL4228565)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460429BDBM50460429(CHEMBL4229142)
Affinity DataIC50: 47nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460416BDBM50460416(CHEMBL4225063)
Affinity DataIC50: 52nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460429BDBM50460429(CHEMBL4229142)
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460418BDBM50460418(CHEMBL4224735)
Affinity DataIC50: 57nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460417BDBM50460417(CHEMBL4226126)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458324BDBM50458324(CHEMBL4202863)
Affinity DataIC50: 74nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460416BDBM50460416(CHEMBL4225063)
Affinity DataIC50: 76nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460427BDBM50460427(CHEMBL4225111)
Affinity DataIC50: 85nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460428BDBM50460428(CHEMBL4228723)
Affinity DataIC50: 112nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460420BDBM50460420(CHEMBL4228565)
Affinity DataIC50: 127nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460416BDBM50460416(CHEMBL4225063)
Affinity DataIC50: 132nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 156nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460433BDBM50460433(CHEMBL4227494)
Affinity DataIC50: 166nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458324BDBM50458324(CHEMBL4202863)
Affinity DataIC50: 168nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460420BDBM50460420(CHEMBL4228565)
Affinity DataIC50: 176nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458324BDBM50458324(CHEMBL4202863)
Affinity DataIC50: 219nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460415BDBM50460415(CHEMBL4227758)
Affinity DataIC50: 249nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460425BDBM50460425(CHEMBL4226835)
Affinity DataIC50: 269nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460426BDBM50460426(CHEMBL4225960)
Affinity DataIC50: 312nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50460420BDBM50460420(CHEMBL4228565)
Affinity DataIC50: 354nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458324BDBM50458324(CHEMBL4202863)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458324BDBM50458324(CHEMBL4202863)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-Leu-GlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed