Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002601
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant PI3K-deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3K-delta (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10 mins in presence of [gamma-32P]ATP by radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 160nMAssay Description:Inhibition of PI3K-delta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460339(CHEMBL4229035)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460340(CHEMBL4228200)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460339(CHEMBL4229035)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PI3K-delta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460340(CHEMBL4228200)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K-delta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of PI3K-gamma (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PI3K-beta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460339(CHEMBL4229035)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 2.55E+5nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460340(CHEMBL4228200)
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460340(CHEMBL4228200)
Affinity DataIC50: 3.55E+5nMAssay Description:Inhibition of PI3K-beta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
India Academy of Scientific & Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50460339(CHEMBL4229035)
Affinity DataIC50: 4.30E+5nMAssay Description:Inhibition of PI3K-beta (unknown origin) by cell free biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed