Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50002942
TargetHistone deacetylase 8(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  3.41E+5nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataEC50:  180nMAssay Description:Inhibition of HDAC in human cell lysates using fluoro-substrate peptide/fluoro-deacetylated peptide as substrate incubated for 20 mins measured at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  2.02E+4nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataEC50:  30nMAssay Description:Inhibition of HDAC in human cell lysates using fluoro-substrate peptide/fluoro-deacetylated peptide as substrate incubated for 20 mins measured at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  350nMAssay Description:Inhibition of HDAC in human cell lysates using fluoro-substrate peptide/fluoro-deacetylated peptide as substrate incubated for 20 mins measured at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed