Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50001606
TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation at PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287311(CHEMBL4176968)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287389(CHEMBL4174767)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287453(CHEMBL4163300)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287311(CHEMBL4176968)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287449(CHEMBL4176181)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287313(CHEMBL4168991)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287329(CHEMBL4163009)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287451(CHEMBL4172357)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287459(CHEMBL4171309)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287389(CHEMBL4174767)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287313(CHEMBL4168991)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287454(CHEMBL4171202)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287450(CHEMBL4161067)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287448(CHEMBL4172800)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287456(CHEMBL4159532)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287314(CHEMBL4167907)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287458(CHEMBL4163414)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287452(CHEMBL4175767)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287388(CHEMBL4167845)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287308(CHEMBL4164478)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287387(CHEMBL4162124)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287455(CHEMBL4170153)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287457(CHEMBL4174644)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 77nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells using [14C] oleic acid as substrate measured after 20 mins by phosphorimaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287447(CHEMBL4171021)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287320(CHEMBL4166344)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287311(CHEMBL4176968)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287315(CHEMBL4159930)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287330(CHEMBL4166868)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287389(CHEMBL4174767)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287313(CHEMBL4168991)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287309(CHEMBL4166743)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287320(CHEMBL4166344)
Affinity DataIC50: 251nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287320(CHEMBL4166344)
Affinity DataIC50: 631nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287330(CHEMBL4166868)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287312(CHEMBL4159638)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287312(CHEMBL4159638)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287446(CHEMBL4164949)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant human DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and C10-CoA as substrate pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by QPatch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using DEX as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using diclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) by QPatch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using phenacetin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ACAT2 (unknown origin) by radiometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin) by QPatch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50287310(CHEMBL4173715)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human DGAT2 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
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