Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50002378
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 80nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457924(CHEMBL4208224)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457923(CHEMBL4209588)
Affinity DataIC50: 500nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457926(CHEMBL4214496)
Affinity DataIC50: 800nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457928(CHEMBL4213146)
Affinity DataIC50: 900nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457925(CHEMBL4207316)
Affinity DataIC50: 900nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457925(CHEMBL4207316)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457927(CHEMBL4208745)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457924(CHEMBL4208224)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457927(CHEMBL4208745)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457923(CHEMBL4209588)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457928(CHEMBL4213146)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457926(CHEMBL4214496)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed