Compile Data Set for Download or QSAR
Report error Found 267 Enz. Inhib. hit(s) with all data for entry = 50000617
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255290(CHEMBL4093081)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255294(CHEMBL4090312)
Affinity DataEC50:  8.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255390(CHEMBL4091029)
Affinity DataEC50:  600nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255291(CHEMBL4060017)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at mGlu4 assessed as decrease in PF-induced presynaptic calcium amplitude in rat coronal slices by Fluo-4FF-AM dye based fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataEC50:  200nMAssay Description:Agonist activity at mGlu4 in C57/Bl6 mouse GP neurons assessed as inhibition of striatopallidal GABAergic inhibitory postsynaptic current amplitude b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255338(CHEMBL4083240)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255336(CHEMBL4064187)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255333(CHEMBL4082270)
Affinity DataEC50:  2.41E+5nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  490nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255294(CHEMBL4090312)
Affinity DataEC50:  8.80E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255333(CHEMBL4082270)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255293(CHEMBL4094636)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255403(CHEMBL4101241)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255335(CHEMBL4065496)
Affinity DataEC50:  7.70E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM196906(US9212196, Derivative 2)
Affinity DataEC50:  110nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255337(CHEMBL4063142)
Affinity DataEC50:  440nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255341(CHEMBL4075070)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255340(CHEMBL4072316)
Affinity DataEC50:  500nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255341(CHEMBL4075070)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255342(CHEMBL4063720)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255346(CHEMBL4085327)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255347(CHEMBL4081842)
Affinity DataEC50:  720nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255348(CHEMBL4085558)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255349(CHEMBL4093305)
Affinity DataEC50:  8.50E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255350(CHEMBL4072587)
Affinity DataEC50:  5.10E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255368(CHEMBL4066711)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255337(CHEMBL4063142)
Affinity DataEC50:  5.70E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255341(CHEMBL4075070)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255334(CHEMBL4094241)
Affinity DataEC50:  5.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255370(CHEMBL4079075)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255293(CHEMBL4094636)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255335(CHEMBL4065496)
Affinity DataEC50:  2.50E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255387(CHEMBL4086929)
Affinity DataEC50:  6.10E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255294(CHEMBL4090312)
Affinity DataEC50:  8.40E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255388(CHEMBL4093492)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255389(CHEMBL4072781)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255336(CHEMBL4064187)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255337(CHEMBL4063142)
Affinity DataEC50:  1.54E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255403(CHEMBL4101241)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255338(CHEMBL4083240)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255406(CHEMBL4088782)
Affinity DataEC50:  640nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255290(CHEMBL4093081)
Affinity DataEC50:  3.98E+4nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255391(CHEMBL4082813)
Affinity DataEC50:  2.77E+5nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255341(CHEMBL4075070)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255346(CHEMBL4085327)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50255334(CHEMBL4094241)
Affinity DataEC50:  4.75E+3nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2019
Entry Details Article
PubMed
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