Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50002178
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454683(CHEMBL4205552)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454700(CHEMBL4212341)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454681(CHEMBL4210463)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454676(CHEMBL4210856)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454696(CHEMBL4215506)
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454683(CHEMBL4205552)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454695(CHEMBL4203006)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454684(CHEMBL4204840)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454701(CHEMBL4211316)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454678(CHEMBL4212465)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454699(CHEMBL4208086)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454679(CHEMBL4212716)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454698(CHEMBL4206180)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454700(CHEMBL4212341)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454682(CHEMBL4213903)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454676(CHEMBL4210856)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454699(CHEMBL4208086)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454696(CHEMBL4215506)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454681(CHEMBL4210463)
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454678(CHEMBL4212465)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454695(CHEMBL4203006)
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454697(CHEMBL4202666)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454701(CHEMBL4211316)
Affinity DataIC50: 7.84E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454698(CHEMBL4206180)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454684(CHEMBL4204840)
Affinity DataIC50: 8.82E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454682(CHEMBL4213903)
Affinity DataIC50: 9.21E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454679(CHEMBL4212716)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454697(CHEMBL4202666)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454677(CHEMBL4216007)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454677(CHEMBL4216007)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454680(CHEMBL4209915)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 cells assessed as reduction in prostaglandin produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Delhi Institute of Pharmaceutical Sciences and Research (Dipsar)

Curated by ChEMBL
LigandPNGBDBM50454680(CHEMBL4209915)
Affinity DataIC50: 5.82E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in Prostaglandin production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed