Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50002170
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 5nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production incubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50634630(NLRP3 Compound 4)
Affinity DataIC50: 5nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production incubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50634627(NLRP3 Compound 1)
Affinity DataIC50: 6nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production incubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50634629(NLRP3 Compound 3)
Affinity DataIC50: 6nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production incubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50634628(NLRP3 Compound 2)
Affinity DataIC50: 7nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production incubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50: 8nMAssay Description:Inhibition of NLRP3 in human monocyte derived macrophages assessed as reduction in LPS-induced IL-1beta production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)