Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50019131
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615577(CHEMBL5281882)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369240(GANAXOLONE)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615577(CHEMBL5281882)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369240(GANAXOLONE)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615576(CHEMBL5282680)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615572(CHEMBL5283818)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615573(CHEMBL5290461)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615574(CHEMBL5272953)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50615575(CHEMBL5276729)
Affinity DataIC50: 5.17E+4nMAssay Description:Inhibition of GluN1/GluN2B NMDA receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed