Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50002035
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  36nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  245nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  300nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  47nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  77nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  92nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  105nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  20nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  61nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  17nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  148nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  112nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  2.19E+3nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  99nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  72nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  162nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  72nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  104nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  80nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  66nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  21nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  89nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  116nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  104nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  280nMAssay Description:Binding affinity to BRD2 bromodomain 2 (348 to 455 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataEC50:  480nMAssay Description:Inhibition of BRD2 in human HD-MB03 cells assessed as reduction in c-Myc protein expression after 72 hrs by Hoechst 33342 staining based immunofluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  61nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  131nMAssay Description:Binding affinity to BRD2 bromodomain 1 (74 to 194 residues) (unknown origin) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  74nMAssay Description:Binding affinity to His-tagged BRD2 bromodomain 2 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50028142(CHEMBL2177300)
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed