Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50019130
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615563(CHEMBL5273665)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 30 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50608294(CHEMBL3949465)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 30 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615565(CHEMBL4576664)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50351632(CHEMBL498769)
Affinity DataIC50: 6nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615556(CHEMBL5265812)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615557(CHEMBL5287421)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615553(CHEMBL5274074)
Affinity DataIC50: 13nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615561(CHEMBL5274092)
Affinity DataIC50: 15nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615564(CHEMBL5282538)
Affinity DataIC50: 18nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 30 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615560(CHEMBL5268193)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using peptide as substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615566(CHEMBL5275718)
Affinity DataIC50: 20nMAssay Description:Inhibition of human c-Met using poly tyrosine as substrate preincubated for 5 mins followed by substrate addition in presence of ATP and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly Tyrosine peptide as substrate in presence of ATP incubated for 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615559(CHEMBL5288803)
Affinity DataIC50: 30nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615555(CHEMBL5270849)
Affinity DataIC50: 30nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615568(CHEMBL5280503)
Affinity DataIC50: 50nMAssay Description:Inhibition of human c-Met using poly tyrosine as substrate preincubated for 5 mins followed by substrate addition in presence of ATP and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM222078(6-Chloro-3-((2-(2,4-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using peptide as substrate in presence of ATP incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615567(CHEMBL5287277)
Affinity DataIC50: 80nMAssay Description:Inhibition of human c-Met using poly tyrosine as substrate preincubated for 5 mins followed by substrate addition in presence of ATP and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM222456(N-(3-fluoro-4-((2-(4-(3-(4-methylpiperazin-1-yl) p...)
Affinity DataIC50: 110nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 135nMAssay Description:Inhibition of wild type ALK (unknown origin) using biotin-TK peptide as substrate in presence of ATP incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM222456(N-(3-fluoro-4-((2-(4-(3-(4-methylpiperazin-1-yl) p...)
Affinity DataIC50: 190nMAssay Description:Inhibition of VEGFR-2 (unknown origin) kinase activity using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615554(CHEMBL5285153)
Affinity DataIC50: 460nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615570(CHEMBL5280248)
Affinity DataIC50: 560nMAssay Description:Inhibition of His6-tagged recombinant human c-Met (974 to end residues) using 5FAM-KKK-SPGEYVNIGFG-NH2 as substrate in presence of ATP incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 578nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using biotin-TK peptide as substrate in presence of ATP incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 651nMAssay Description:Inhibition of ALK C1156Y mutant (unknown origin) using biotin-TK peptide as substrate in presence of ATP incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615558(CHEMBL5270194)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615569(CHEMBL5274483)
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using peptide as substrate in presence of 33P-ATP incubated for 20 to 30 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615571(CHEMBL5266922)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of c-Met (unknown origin) phosphorylation using Tyr2 peptide as substrate in presence of ATP incubated for 1 hrs by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM53940(2-chloro-5-[5-[(Z)-[1-(4-methoxycarbonylphenyl)-3,...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50615562(CHEMBL5288034)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of c-Met (unknown origin) kinase activity using biotinylated poly-tyrosine as substrate in presence of ATP incubated for 1 hr by AlphaQues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed