Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50001134
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to ferrous form of human recombinant IDO-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataKd:  150nMAssay Description:Binding affinity to ferric form of human recombinant IDO-1 in absence of oxygen and presence of tryptophanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataKd:  320nMAssay Description:Binding affinity to ferric form of human recombinant IDO-1 in absence of oxygenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataKd:  160nMAssay Description:Binding affinity to ferric form of human recombinant IDO-1 in absence of oxygenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataKd:  2.23E+4nMAssay Description:Binding affinity to ferric form of human recombinant IDO-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to ferric form of human recombinant IDO-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to ferrous form of human recombinant IDO-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312073(US9603836, Compound 9 | 3-(6-bromo-5-fluoro- 1H-in...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312076(US9603836, Compound 11 | 3-(5-bromo-1H-indol-3- yl...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312084(US9603836, Compound 19 | 3-(6-bromo-1H-indol-3- yl...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312072(US9603836, Compound 7 | 3-(6-chloro-5-fluoro-1H- i...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389161(US9949951, 8 | (R)-3-(6-chloro-5- fluoro-1H-indol-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312074(US9603836, Compound 10 | (R)-3-(6-bromo-5- fluoro-...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312069(US9603836, Compound 5 | 3-(5-chloro-1H-indol-3- yl...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human THP1 cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389150(US9949951, 14 | 3-(2,5-dioxopyrrolidin- 3-yl)-1H-i...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of mouse IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312088(US9603836, Compound 24 | 3-(6-fluoronaphthanlen- 1...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389157(US9949951, 22 | 3-(2,5-dioxopyrrolidin- 3-yl)-1H-i...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human THP1 cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312080(US9603836, Compound 15 | 3-(5,6-difluoro-1H- indol...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312083(US9603836, Compound 18 | 3-(6-chloro-1H-indol-3- y...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312070(US9603836, Compound 6 | (-)-(R)-3-(5-chloro-1H- in...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine production after 24 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM73346(MLS000099368 | SMR000071516 | cid_363326 | 3-(1H-i...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312082(US9603836, Compound 17 | 3-(6-fluoro-1H-indol-3- y...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312089(US9603836, Compound 25 | 3-(7-fluoronaphthanlen- 1...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine production after 24 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of mouse IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312075(US9603836, Compound 10a | US9949951, 10a)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269943(CHEMBL4073619)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312087(US9603836, Compound 23 | 3-(naphthalen-1-yl)- pyrr...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312081(US9603836, Compound 16 | 3-(5-fluoro-6-methyl- 1H-...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269915(CHEMBL4080434)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269916(CHEMBL4098167)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269931(CHEMBL4099318)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
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