Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 50001534
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283488(CHEMBL4171274)
Affinity DataEC50:  1.05E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283478(CHEMBL4164141)
Affinity DataEC50: <3.16E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283479(CHEMBL4165248)
Affinity DataEC50: <3.16E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283483(CHEMBL2361777)
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283481(CHEMBL4160675)
Affinity DataEC50:  741nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283493(CHEMBL4164496)
Affinity DataEC50:  2.75E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50:  646nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283489(CHEMBL4168668)
Affinity DataEC50:  603nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50:  2.60E+3nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283478(CHEMBL4164141)
Affinity DataEC50:  490nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283481(CHEMBL4160675)
Affinity DataEC50:  2.14E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283482(CHEMBL4172374)
Affinity DataEC50:  2.30E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283490(CHEMBL4172016)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283489(CHEMBL4168668)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283492(CHEMBL4165644)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283483(CHEMBL2361777)
Affinity DataEC50:  3.30E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283487(CHEMBL4162576)
Affinity DataEC50:  146nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  1.50E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283490(CHEMBL4172016)
Affinity DataEC50:  1.02E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu1 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  3.20E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50:  650nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283489(CHEMBL4168668)
Affinity DataEC50:  2.90E+3nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283485(CHEMBL4161084)
Affinity DataEC50:  1.70E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283484(CHEMBL4175868)
Affinity DataEC50:  1.70E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu6 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283492(CHEMBL4165644)
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283486(CHEMBL4161818)
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu3 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50:  52nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283493(CHEMBL4164496)
Affinity DataEC50:  2.80E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283483(CHEMBL2361777)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283479(CHEMBL4165248)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283489(CHEMBL4168668)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283491(CHEMBL1585091)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283487(CHEMBL4162576)
Affinity DataEC50:  125nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283483(CHEMBL2361777)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283478(CHEMBL4164141)
Affinity DataEC50:  490nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283483(CHEMBL2361777)
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283481(CHEMBL4160675)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283478(CHEMBL4164141)
Affinity DataEC50:  480nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283486(CHEMBL4161818)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50116515(CHEMBL3609729)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50: <1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283485(CHEMBL4161084)
Affinity DataEC50:  1.74E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283478(CHEMBL4164141)
Affinity DataEC50:  479nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283481(CHEMBL4160675)
Affinity DataEC50:  891nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283480(CHEMBL4175784)
Affinity DataEC50:  1.48E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283484(CHEMBL4175868)
Affinity DataEC50:  1.66E+3nMAssay Description:Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283479(CHEMBL4165248)
Affinity DataEC50:  2.04E+3nMAssay Description:Positive allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2020
Entry Details Article
PubMed
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