Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50001428
TargetBaculoviral IAP repeat-containing protein 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant human His-tagged cIAP1 (Leu250 to Gly350 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279265(CHEMBL4162041)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human His-tagged cIAP1 (Leu250 to Gly350 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human His-tagged cIAP1 (Leu250 to Gly350 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged cIAP1 (Leu250 to Gly350 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50328152(N-(2-hydroxyethyl)-3-(6-(4-(trifluoromethoxy)pheny...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50325999(3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed