Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50019124
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615534(CHEMBL5271686)
Affinity DataIC50: 11nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50335054(2-Amino-4-[2-(5-phosphono)furanyl]-5-ethoxycarbony...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50560999(CHEMBL4784789)
Affinity DataIC50: 31nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615539(CHEMBL5280779)
Affinity DataIC50: 32nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21 (DE3) measured after 48 hrs by spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615530(CHEMBL5278857)
Affinity DataIC50: 34nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615531(CHEMBL5272081)
Affinity DataIC50: 60nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50303854(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50101435(CHEMBL3393956)
Affinity DataIC50: 100nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615533(CHEMBL5277487)
Affinity DataIC50: 140nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50095256((6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-4-fluor...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM4626(CHEMBL301018 | N-(3-chloro-4-fluorophenyl)-6,7-dim...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615532(CHEMBL5286087)
Affinity DataIC50: 370nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50181324(N-(7-(3-aminophenyl)-5-methoxybenzo[d]oxazol-2-yl)...)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50277660({5-[6-Amino-9-(2,2-dimethyl-propyl)-2-methylsulfan...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50449198(CHEMBL3127628)
Affinity DataIC50: 990nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM18137(adenosine 5 -monophosphate | CHEMBL752 | [(2R,3S,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50095261(4-(3'-chloroanilino)-6,7-diethoxyquinazoline hydro...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615528(CHEMBL5269366)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615529(CHEMBL1230892)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50449167(CHEMBL3127767)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50449166(CHEMBL3127629)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50449192(CHEMBL3127755)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50611791(CHEMBL1521269)
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50449201(CHEMBL3127747)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50316379(US9273021, 4 | 1,1'-(1,3,7,9-Tetrahydroxydibenzofu...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM22579(Aminoimidazole-4-carboxamide ribonucleotide | CHEM...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615538(CHEMBL3287951)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615535(CHEMBL5291240)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615537(CHEMBL5269870)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50615536(CHEMBL5289074)
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50303854(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50277609([5-(6-Amino-9-isobutyl-2-methylsulfanyl-9H-purin-8...)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
University Institute of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50277565({5-[6-Amino-9-(2,2-dimethyl-propyl)-9H-purin-8-yl]...)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed