Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50019122
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50237597(7-hydroxy-3-(2-oxo-2H-chromen-7-yloxy)chromen-2-on...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615527(CHEMBL5279622)
Affinity DataIC50: 30nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu,Tyr) at 4:1 ratio as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50269808(6,7-dihydroxy-3,7'-dicoumaryl ether | CHEMBL462972)
Affinity DataIC50: 50nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50241949(Daphnoretin | NSC-291852 | 7-hydroxy-6-methoxy-3,7...)
Affinity DataIC50: 86nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615526(CHEMBL5289616)
Affinity DataIC50: 107nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu,Tyr) at 4:1 ratio as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615522(CHEMBL5287026)
Affinity DataIC50: 231nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615521(CHEMBL5266421)
Affinity DataIC50: 760nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase using pNPG as substrate incubated for 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 7.67E+3nMAssay Description:Inhibition of EGFR (unknown origin) using (Glu, Tyr) 4:1 as substrate incubated for [gamma-32P]-ATP incubated for 60 mins by scintillation counter an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of PKA (unknown origin) using Kemptide as substrate incubated for [gamma-32P]-ATP incubated for 5 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM173549(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of Baker's yeast alpha-glucosidase using pNPG as substrate assessed as release of p-nitrophenol preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615512(CHEMBL3264730)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615523(CHEMBL5287344)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM173561(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKC (unknown origin) using acetylated myelin basic protein (4 to 14 residues) as substrate incubated for [gamma-32P]-ATP incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM173548(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of Baker's yeast alpha-glucosidase using pNPG as substrate assessed as release of p-nitrophenol preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615511(CHEMBL3264731)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615518(CHEMBL3264727)
Affinity DataIC50: 5.71E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615517(CHEMBL3264724)
Affinity DataIC50: 8.36E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615516(CHEMBL3264725)
Affinity DataIC50: 8.41E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615520(CHEMBL3264729)
Affinity DataIC50: 9.14E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615525(CHEMBL5285878)
Affinity DataIC50: 9.48E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615509(CHEMBL4163473)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM173547(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Baker's yeast alpha-glucosidase using pNPG as substrate assessed as release of p-nitrophenol preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM512905(acs.jmedchem.1c00409_ST.500)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615515(CHEMBL3264726)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetDNA polymerase beta(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615524(CHEMBL5284427)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615519(CHEMBL3264728)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615510(CHEMBL5289921)
Affinity DataIC50: 1.51E+5nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615514(CHEMBL3264733)
Affinity DataIC50: 2.21E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50615513(CHEMBL3264720)
Affinity DataIC50: 3.86E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 7.75E+5nMAssay Description:Inhibition of Baker's yeast alpha-glucosidase using pNPG as substrate assessed as release of p-nitrophenol preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 9.06E+5nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed