Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50001420
TargetTranslocator protein(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279019(CHEMBL1315992)
Affinity DataKd:  40nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKd:  11nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279015(CHEMBL4174207)
Affinity DataKd:  61nMAssay Description:Binding affinity to C-terminal DDK-tagged human recombinant full-length TSPO expressed in HEK293 cells by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataIC50: 7.5nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279019(CHEMBL1315992)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279015(CHEMBL4174207)
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279020(CHEMBL4170783)
Affinity DataIC50: 55nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279014(CHEMBL4175877)
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279021(CHEMBL4166954)
Affinity DataIC50: 1.67E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279022(CHEMBL4160135)
Affinity DataIC50: 2.23E+3nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50279018(CHEMBL4159052)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]PK11195 from TSPO in Sprague-Dawley rat cerebral cortex membranes after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed