Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50001418
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278990(CHEMBL4164524)
Affinity DataIC50: 153nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 424nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278968(CHEMBL4164186)
Affinity DataIC50: 648nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278969(CHEMBL4160790)
Affinity DataIC50: 759nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278968(CHEMBL4164186)
Affinity DataIC50: 828nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278986(CHEMBL4161860)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278969(CHEMBL4160790)
Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278984(CHEMBL4168710)
Affinity DataIC50: 4.02E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278983(CHEMBL4172510)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278990(CHEMBL4164524)
Affinity DataIC50: 4.59E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278987(CHEMBL4165299)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278983(CHEMBL4172510)
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278984(CHEMBL4168710)
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278970(CHEMBL4175914)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278985(CHEMBL4172060)
Affinity DataIC50: 8.41E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278987(CHEMBL4165299)
Affinity DataIC50: 8.85E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278988(CHEMBL4163781)
Affinity DataIC50: 9.96E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278986(CHEMBL4161860)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278970(CHEMBL4175914)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278988(CHEMBL4163781)
Affinity DataIC50: 9.97E+4nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278990(CHEMBL4164524)
Affinity DataKi:  39nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278986(CHEMBL4161860)
Affinity DataKi:  53nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278968(CHEMBL4164186)
Affinity DataKi:  157nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278987(CHEMBL4165299)
Affinity DataKi:  205nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278969(CHEMBL4160790)
Affinity DataKi:  259nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278984(CHEMBL4168710)
Affinity DataKi:  288nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278970(CHEMBL4175914)
Affinity DataKi:  355nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278983(CHEMBL4172510)
Affinity DataKi:  404nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed