Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50000152
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241669(CHEMBL4083139)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50035880(CHEMBL1437990)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241667(CHEMBL576076 | 8-Dimethylaminoadenine)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241663(CHEMBL1441434)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241664(CHEMBL4104686)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241668(CHEMBL569241)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241665(CHEMBL111812)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50241666(CHEMBL4102823)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed