Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50019112
TargetTrypanothione synthetase(Crithidia fasciculata)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615400BDBM50615400(CHEMBL4092938)
Affinity DataIC50: 30nMAssay Description:Inhibition of Crithidia fasciculata His tagged TryS in presence of ATP by LDH/PK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615386BDBM50615386(CHEMBL5283195)
Affinity DataIC50: 200nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50070270BDBM50070270(Pentanedioic acid bis-[(3-{4-bromo-2-[3-(4-methyl-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096500BDBM50096500(N,N'-Bis-(3-phenyl-propyl)-N,N'-bis-[3-(3-phenyl-p...)
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615388BDBM50615388(CHEMBL5280255)
Affinity DataIC50: 600nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615401BDBM50615401(CHEMBL5081809)
Affinity DataIC50: 750nMAssay Description:Inhibition of Trypanosoma brucei TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615389BDBM50615389(CHEMBL5283514)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615385BDBM50615385(CHEMBL5270809)
Affinity DataIC50: 930nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615383BDBM50615383(CHEMBL5273760)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR expressed in escherichia coli SG5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240622BDBM50240622(N1,N2-bis(dihydrocaffeoyl)spermine | 3-(3,4-Dihydr...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615394BDBM50615394(CHEMBL5266592)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096496BDBM50096496(N1,N4-bis(3-aminopropyl)-N1,N4-bis(3-phenylpropyl)...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096493BDBM50096493(N1,N4-bis(3-phenylpropyl)-N1-(3-(3-phenylpropylami...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 77970BDBM77970(CLOMIPRAMINE HYDROCHLORIDE | CHLORIMIPRAMINE | 3-(...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR measured after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615387BDBM50615387(CHEMBL5286658)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408797BDBM50408797(CHEMBL151228)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 78434BDBM78434(2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phen...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Trypanosoma brucei TryRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285025BDBM50285025(N-Naphthalen-2-ylmethyl-N'-{3-[(naphthalen-2-ylmet...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096498BDBM50096498(N1,N4-bis(3-(3-phenylpropylamino)propyl)butane-1,4...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615395BDBM50615395(CHEMBL5280891)
Affinity DataKi:  1.59E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009371BDBM50009371(1, 12-DB-3-4-3 | N,N'-Bis-(3-benzylamino-propyl)-b...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015214BDBM50015214(N-(4-Hydroxy-phenyl)-acetamide | 6-chloro-2-methox...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615396BDBM50615396(CHEMBL311566)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096497BDBM50096497(N1-(3-aminopropyl)-N4-(3-(3-phenylpropylamino)prop...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087158BDBM50087158(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087155BDBM50087155(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615381BDBM50615381(CHEMBL5269894)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR expressed in escherichia coli in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615384BDBM50615384(CHEMBL80264)
Affinity DataKi:  8.50E+4nMAssay Description:Inhibition of Crithidia fasciculata TryR overexpressed in escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615399BDBM50615399(CHEMBL82315)
Affinity DataKi:  8.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615398BDBM50615398(CHEMBL77450)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant by TR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615382BDBM50615382(CHEMBL211029)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma brucei TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184783BDBM50184783(N*1*-(3-Amino-propyl)-N*1*-naphthalen-2-ylmethyl-b...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615397BDBM50615397(CHEMBL210576)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184788BDBM50184788(benzyl 4-aminobutyl(3-aminopropyl)carbamate | (4-A...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615393BDBM50615393(CHEMBL2008816)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615391BDBM50615391(CHEMBL5277812)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615392BDBM50615392(CHEMBL2009956)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Univ Paris Sud

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615390BDBM50615390(CHEMBL210734)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of Trypanosoma cruzi TryR assessed as inhibition constant in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed