Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000835
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261555(CHEMBL4088694)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261554(CHEMBL4092300)
Affinity DataEC50:  1.33E+3nMAssay Description:Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261553(CHEMBL4087989)
Affinity DataEC50:  1.44E+3nMAssay Description:Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 0.820nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen-related receptor gamma(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Diphenylolpropane | Bisphenol A (BPA) | US9688816,...)
Affinity DataIC50: 4.90nMAssay Description:Binding affinity to human ERRgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen-related receptor gamma(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 62nMAssay Description:Binding affinity to human ERRgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261553(CHEMBL4087989)
Affinity DataIC50: 154nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261553(CHEMBL4087989)
Affinity DataIC50: 169nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 226nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261555(CHEMBL4088694)
Affinity DataIC50: 294nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261555(CHEMBL4088694)
Affinity DataIC50: 306nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 341nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261551(CHEMBL4094003)
Affinity DataIC50: 915nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261554(CHEMBL4092300)
Affinity DataIC50: 939nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261554(CHEMBL4092300)
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 1.53E+3nMAssay Description:Antagonist activity at full length ERbeta (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261556(CHEMBL4105062)
Affinity DataIC50: 1.65E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261557(CHEMBL4071813)
Affinity DataIC50: 1.68E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261551(CHEMBL4094003)
Affinity DataIC50: 1.69E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261556(CHEMBL4105062)
Affinity DataIC50: 1.98E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261557(CHEMBL4071813)
Affinity DataIC50: 2.53E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261558(CHEMBL4071506)
Affinity DataIC50: 2.65E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261552(CHEMBL4066690)
Affinity DataIC50: 3.51E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261552(CHEMBL4066690)
Affinity DataIC50: 5.34E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261551(CHEMBL4094003)
Affinity DataIC50: 9.39E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed