Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50000827
TargetDNA-dependent protein kinase catalytic subunit(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50261349(CHEMBL4073785)
Affinity DataIC50: 2nMAssay Description:Inhibition of DNA-PK in human HeLa nuclear extracts incubated for 40 mins using calf thymus DNA and fluoroscein-p53[Ser15]-peptide by Lanthascreen ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50261349(CHEMBL4073785)
Affinity DataIC50: 2nMAssay Description:Inhibition of human DNA-PK catalytic subunit using DNA and [EPPLSQEAFADLWKK] peptide substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human DNA-PK catalytic subunit using DNA and [EPPLSQEAFADLWKK] peptide substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261355(CHEMBL4071376)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261354(CHEMBL4103756)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261337(CHEMBL4074385)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50261329(CHEMBL4077367)
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of human PDE3A by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261339(CHEMBL4079378)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261347(CHEMBL4104565)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50261350(CHEMBL4091681)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of human PDE3A by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50261328(CHEMBL4083912)
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of human PDE3A by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50261351(CHEMBL4062189)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of human PDE3A by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261352(CHEMBL4088661)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261329(CHEMBL4077367)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261348(CHEMBL4075473)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261340(CHEMBL4084755)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50027176(CHEBI:34795 | 2-Acetoxy-Benzoic Acid | 3-Isobutyl-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human PDE3A by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261353(CHEMBL4061587)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261341(CHEMBL4094832)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261338(CHEMBL4071051)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
LigandPNGBDBM50261330(CHEMBL4105146)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of wild type PI3K-delta (unknown origin) assessed as decrease in ATP consumption using phosphotidylinositol bisphosphate and ATP measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed