Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50000826
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261301(CHEMBL4072422)
Affinity DataIC50: 32nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261322(CHEMBL4060424)
Affinity DataIC50: 46nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261327(CHEMBL4083286)
Affinity DataIC50: 50nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 54nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261309(CHEMBL4091125)
Affinity DataIC50: 58nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 63nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261311(CHEMBL4076718)
Affinity DataIC50: 90nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261321(CHEMBL4061450)
Affinity DataIC50: 157nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261308(CHEMBL4099864)
Affinity DataIC50: 174nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261307(CHEMBL4081862)
Affinity DataIC50: 177nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261326(CHEMBL4064091)
Affinity DataIC50: 237nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261300(CHEMBL4084362)
Affinity DataIC50: 403nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261324(CHEMBL4098822)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261323(CHEMBL4087545)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261325(CHEMBL4060556)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50261310(CHEMBL4102181)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2020
Entry Details Article
PubMed