Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50001358
TargetPlatelet-derived growth factor receptor alpha(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRalpha (550 to 1089 end residues) cytoplasmic domain expressed in baculovirus expression system preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal GST tagged human VEGFR3 (798 to 1298 end residues) cytoplasmic domain expressed in baculovirus expression system preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276297(CHEMBL4165429)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRalpha (550 to 1089 end residues) cytoplasmic domain expressed in baculovirus expression system preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276297(CHEMBL4165429)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST tagged human VEGFR3 (798 to 1298 end residues) cytoplasmic domain expressed in baculovirus expression system preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276297(CHEMBL4165429)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276304(CHEMBL4173078)
Affinity DataIC50: 34nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276294(CHEMBL4161991)
Affinity DataIC50: 39nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276303(CHEMBL4166696)
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276295(CHEMBL4169257)
Affinity DataIC50: 46nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276296(CHEMBL4162400)
Affinity DataIC50: 49nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276311(CHEMBL4177112)
Affinity DataIC50: 61nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276308(CHEMBL4164318)
Affinity DataIC50: 61nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276362(CHEMBL4172205)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276297(CHEMBL4165429)
Affinity DataIC50: 69nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276303(CHEMBL4166696)
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276306(CHEMBL4165850)
Affinity DataIC50: 92nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276298(CHEMBL4173756)
Affinity DataIC50: 93nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataIC50: 98nMAssay Description:Inhibition of N-terminal GST tagged human FGFR1 (398 to 822 end residues) cytoplasmic domain expressed in baculovirus expression system preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276294(CHEMBL4161991)
Affinity DataIC50: 105nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276298(CHEMBL4173756)
Affinity DataIC50: 106nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276307(CHEMBL4173817)
Affinity DataIC50: 116nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276309(CHEMBL4176458)
Affinity DataIC50: 135nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276300(CHEMBL4165827)
Affinity DataIC50: 138nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276364(CHEMBL4161351)
Affinity DataIC50: 242nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276311(CHEMBL4177112)
Affinity DataIC50: 257nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276295(CHEMBL4169257)
Affinity DataIC50: 385nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276304(CHEMBL4173078)
Affinity DataIC50: 431nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276299(CHEMBL4163106)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276296(CHEMBL4162400)
Affinity DataIC50: 647nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276362(CHEMBL4172205)
Affinity DataIC50: 809nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276302(CHEMBL4176039)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276306(CHEMBL4165850)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276308(CHEMBL4164318)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276299(CHEMBL4163106)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276297(CHEMBL4165429)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of N-terminal GST tagged human FGFR1 (398 to 822 end residues) cytoplasmic domain expressed in baculovirus expression system preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed