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Compile Data Set for Download or QSAR
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Found
10
Enz. Inhib. hit(s) with all data for entry = 50022562
Target
DNA topoisomerase 2-alpha
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM22984
(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
DNA topoisomerase 2-alpha
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM22984
(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 17nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
DNA topoisomerase 2-alpha
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM22984
(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
DNA topoisomerase 2-alpha
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM22984
(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 41nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
DNA topoisomerase 2-alpha
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM22984
(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 124nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Bromodomain-containing protein 4
(Mouse)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM50365262
(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Bromodomain-containing protein 4
(Mouse)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM50365262
(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Bromodomain-containing protein 4
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM50365262
(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.22E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Bromodomain-containing protein 4
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM50365262
(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.36E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Bromodomain-containing protein 4
(Human)
Erasmus University Medical Center
Curated by
ChEMBL
Ligand
BDBM50365262
(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.42E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/13/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL