Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50000819
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261048(CHEMBL4062501)
Affinity DataIC50: 900nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261064(CHEMBL4100146)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261048(CHEMBL4062501)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261064(CHEMBL4100146)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053590(N-(4-Chloro-phenyl)-guanidine | N-(4-chlorophenyl)...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261064(CHEMBL4100146)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50100962(1N-amino(immino)methyl-4-methylaniline | N-(4-meth...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261063(CHEMBL1160763)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261063(CHEMBL1160763)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053608(N-(3-Chloro-phenyl)-guanidine | 1N-amino(immino)me...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261048(CHEMBL4062501)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50100962(1N-amino(immino)methyl-4-methylaniline | N-(4-meth...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053590(N-(4-Chloro-phenyl)-guanidine | N-(4-chlorophenyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50100962(1N-amino(immino)methyl-4-methylaniline | N-(4-meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261063(CHEMBL1160763)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053608(N-(3-Chloro-phenyl)-guanidine | 1N-amino(immino)me...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053590(N-(4-Chloro-phenyl)-guanidine | N-(4-chlorophenyl)...)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261065(CHEMBL1160766)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261065(CHEMBL1160766)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053620(1N-amino(immino)methylaniline | 1-phenylguanidine ...)
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261065(CHEMBL1160766)
Affinity DataIC50: 4.83E+4nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053608(N-(3-Chloro-phenyl)-guanidine | 1N-amino(immino)me...)
Affinity DataIC50: 6.05E+4nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053620(1N-amino(immino)methylaniline | 1-phenylguanidine ...)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261049(N-(4-Benzylphenyl)Guanidine | CHEMBL272259)
Affinity DataIC50: 9.62E+4nMAssay Description:Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053620(1N-amino(immino)methylaniline | 1-phenylguanidine ...)
Affinity DataIC50: 9.98E+4nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261049(N-(4-Benzylphenyl)Guanidine | CHEMBL272259)
Affinity DataIC50: 4.53E+5nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50261049(N-(4-Benzylphenyl)Guanidine | CHEMBL272259)
Affinity DataIC50: 7.62E+5nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50420178(GUANIDINE)
Affinity DataIC50: 2.20E+6nMAssay Description:Inhibition of OCT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2020
Entry Details Article
PubMed