Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50000817
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260997BDBM50260997(CHEMBL4073607)
Affinity DataIC50: 0.767nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261002BDBM50261002(CHEMBL4059968)
Affinity DataIC50: 0.820nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260978BDBM50260978(CHEMBL4091475)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260979BDBM50260979(CHEMBL4069535)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260983BDBM50260983(CHEMBL4089060)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260976BDBM50260976(CHEMBL4081186)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260963BDBM50260963(CHEMBL4077821)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260977BDBM50260977(CHEMBL4070565)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260975BDBM50260975(CHEMBL4095852)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260985BDBM50260985(CHEMBL4100428)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260985BDBM50260985(CHEMBL4100428)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261019BDBM50261019(CHEMBL4087320)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261003BDBM50261003(CHEMBL4060971)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261000BDBM50261000(CHEMBL4080357)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260987BDBM50260987(CHEMBL4088347)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260984BDBM50260984(CHEMBL4060868)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261005BDBM50261005(CHEMBL4090659)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261006BDBM50261006(CHEMBL4065909)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261002BDBM50261002(CHEMBL4059968)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260978BDBM50260978(CHEMBL4091475)
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261028BDBM50261028(CHEMBL3398466)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261022BDBM50261022(CHEMBL4069644)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261028BDBM50261028(CHEMBL3398466)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260998BDBM50260998(CHEMBL4096766)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261001BDBM50261001(CHEMBL4098384)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261020BDBM50261020(CHEMBL4068004)
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260986BDBM50260986(CHEMBL4060107)
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260991BDBM50260991(CHEMBL3398476)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260987BDBM50260987(CHEMBL4088347)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260997BDBM50260997(CHEMBL4073607)
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261021BDBM50261021(CHEMBL4096898)
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260977BDBM50260977(CHEMBL4070565)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260989BDBM50260989(CHEMBL3398472)
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261004BDBM50261004(CHEMBL4082852)
Affinity DataIC50: 9.5nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260988BDBM50260988(CHEMBL4096073)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261023BDBM50261023(CHEMBL4088212)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260983BDBM50260983(CHEMBL4089060)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260963BDBM50260963(CHEMBL4077821)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260991BDBM50260991(CHEMBL3398476)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260989BDBM50260989(CHEMBL3398472)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260999BDBM50260999(CHEMBL4099210)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260979BDBM50260979(CHEMBL4069535)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260986BDBM50260986(CHEMBL4060107)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260984BDBM50260984(CHEMBL4060868)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260976BDBM50260976(CHEMBL4081186)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261020BDBM50261020(CHEMBL4068004)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261003BDBM50261003(CHEMBL4060971)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261000BDBM50261000(CHEMBL4080357)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260998BDBM50260998(CHEMBL4096766)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260990BDBM50260990(CHEMBL4087451)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed
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