Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50003225
TargetGlycogen synthase kinase-3 beta(Rat)
Babasaheb Bhimrao Ambedkar University

Curated by ChEMBL
LigandPNGBDBM7497(14-bromo-3,8,18-triazatetracyclo[9.7.0.0^{2,7}.0^{...)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat GSK3beta expressed in Sf9 cells incubated for 30 mins using GS-1 peptide substrate and [gamma-32P]ATP by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Babasaheb Bhimrao Ambedkar University

Curated by ChEMBL
LigandPNGBDBM7336(Paullone Analogue 71 | 13-bromo-3-thia-7,17-diazat...)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat GSK3beta expressed in Sf9 cells incubated for 30 mins using GS-1 peptide substrate and [gamma-32P]ATP by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Babasaheb Bhimrao Ambedkar University

Curated by ChEMBL
LigandPNGBDBM7266(cid_3820 | NSC 664704 | 9-bromopaullone | 14-bromo...)
Affinity DataIC50: 400nMAssay Description:Inhibition of GST-tagged CDK1/cyclin B (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Babasaheb Bhimrao Ambedkar University

Curated by ChEMBL
LigandPNGBDBM7336(Paullone Analogue 71 | 13-bromo-3-thia-7,17-diazat...)
Affinity DataIC50: 600nMAssay Description:Inhibition of GST-tagged CDK1/cyclin B (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Babasaheb Bhimrao Ambedkar University

Curated by ChEMBL
LigandPNGBDBM7497(14-bromo-3,8,18-triazatetracyclo[9.7.0.0^{2,7}.0^{...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-tagged CDK1/cyclin B (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed