Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50000786
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353128BDBM50353128(CHEMBL1231795)
Affinity DataIC50: 15nMAssay Description:Inhibition of EHMT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353128BDBM50353128(CHEMBL1231795)
Affinity DataIC50: 19nMAssay Description:Inhibition of EHMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 100nMAssay Description:Inhibition of EHMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 100nMAssay Description:Inhibition of EHMT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300028BDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 700nMAssay Description:Inhibition of EHMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300028BDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of GST-tagged G9a (685 to 1000 residues) (unknown origin) expressed in Escherichia coli BL21 using biotinylated H3 (1to20 residues) as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260389BDBM50260389(CHEMBL4095401)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378739BDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of EHMT2 (unknown origin) preincubated for 15 mins followed by SAM and biotinylated H3K9 peptide addition measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260389BDBM50260389(CHEMBL4095401)
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of EHMT2 (unknown origin) preincubated for 15 mins followed by SAM and biotinylated H3K9 peptide addition measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260387BDBM50260387(CHEMBL4074394)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260388BDBM50260388(CHEMBL4103578)
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of EHMT2 (unknown origin) preincubated for 15 mins followed by SAM and biotinylated H3K9 peptide addition measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260383BDBM50260383(CHEMBL4089220)
Affinity DataIC50: 9.51E+4nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260385BDBM50260385(CHEMBL4085649)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260384BDBM50260384(CHEMBL4077793)
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260387BDBM50260387(CHEMBL4074394)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of EHMT2 (unknown origin) preincubated for 15 mins followed by SAM and biotinylated H3K9 peptide addition measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260383BDBM50260383(CHEMBL4089220)
Affinity DataIC50: 1.91E+5nMAssay Description:Inhibition of EHMT2 (unknown origin) preincubated for 15 mins followed by SAM and biotinylated H3K9 peptide addition measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260386BDBM50260386(CHEMBL4065774)
Affinity DataIC50: 2.04E+5nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260388BDBM50260388(CHEMBL4103578)
Affinity DataIC50: 7.94E+5nMAssay Description:Inhibition of EHMT1 (unknown origin) preincubated for 5 mins followed by SAM and biotinylated H3K9 peptide addition measured after 120 mins by HTRF a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMed