Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50001341
TargetOxysterols receptor LXR-beta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human LXRbeta LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human PPARdelta LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human PPARalpha LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human RARbeta LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human LXRalpha LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human RXRalpha LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276796(CHEMBL4170306)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of fluormone ES2 green binding to recombinant full length human ERalpha expressed in insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of fluormone ES2 binding to recombinant full length human ERbeta expressed in insect cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276803(CHEMBL4169272)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276805(CHEMBL4166492)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276818(CHEMBL4161346)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276817(CHEMBL4159613)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276834(CHEMBL4163909)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetEstrogen-related receptor gamma(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at ERRgamma (unknown origin) assessed as inhibition of co-activator peptide recruitment by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276816(CHEMBL4166832)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276822(CHEMBL4165363)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276830(CHEMBL4172209)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276811(CHEMBL4172522)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276814(CHEMBL4163054)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276795(CHEMBL4163375)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276835(CHEMBL4173278)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276823(CHEMBL4177113)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276836(CHEMBL4173757)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276812(CHEMBL4164196)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276833(CHEMBL4175927)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276831(CHEMBL4164640)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276824(CHEMBL4169919)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276825(CHEMBL4161594)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276832(CHEMBL4168072)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276810(CHEMBL4161992)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276804(CHEMBL4171282)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276821(CHEMBL4167938)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276815(CHEMBL4171419)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276819(CHEMBL4174736)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276838(CHEMBL4160799)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276813(CHEMBL4170236)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276837(CHEMBL4159675)
Affinity DataIC50: 54nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 103nMAssay Description:Inhibition of fluormone PPARgamma Green binding to recombinant N-terminal GST-tagged human PPARgamma LBD by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid hormone receptor ERR1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276820(CHEMBL4160018)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50: 886nMAssay Description:Antagonist activity at recombinant GST-tagged human ERRbeta LBD assessed as inhibition of fluorescein-labeled coactivator peptide recruitment preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant GST-tagged human RXRalpha LBD assessed as inhibition of 9-cis-retinoic acid-induced fluorescein-labeled coactivato...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant GST-tagged human LXRalpha LBD assessed as inhibition of TO901317-induced fluorescein-labeled coactivator peptide r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fluormone PPARgamma Green binding to recombinant N-terminal GST-tagged human PPARgamma LBD by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at recombinant GST-tagged human LXRbeta LBD assessed as fluorescein-labeled coactivator peptide recruitment preincubated with enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant GST-tagged human PPARalpha LBD assessed as inhibition of GW7647-induced fluorescein-labeled coactivator peptide re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant GST-tagged human RXRbeta LBD assessed as inhibition of all-trans-retinoic acid-induced fluorescein-labeled coactiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetEstrogen-related receptor gamma(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at ERRgamma (unknown origin) assessed as inhibition of co-activator peptide recruitment by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50276797(CHEMBL4174856)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant GST-tagged human PPARdelta LBD assessed as inhibition of GW0742-induced fluorescein-labeled coactivator peptide re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 54 total ) | Next | Last >>
Jump to: