Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50000674
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257775(CHEMBL4100462)
Affinity DataIC50: 2nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257807(CHEMBL4073638)
Affinity DataIC50: 5nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257776(CHEMBL4084005)
Affinity DataIC50: 8nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50: 9nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193000(US9670204, 180 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 12nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192946(US9670204, 141 2-((2-ethyl-6-(1-(2-(3-hydroxyazeti...)
Affinity DataIC50: 22nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192946(US9670204, 141 2-((2-ethyl-6-(1-(2-(3-hydroxyazeti...)
Affinity DataIC50: 27nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192946(US9670204, 141 2-((2-ethyl-6-(1-(2-(3-hydroxyazeti...)
Affinity DataIC50: 27nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192616(US9670204, 115 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 86nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192616(US9670204, 115 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 115nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257794(CHEMBL4084750)
Affinity DataIC50: 122nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192268(US9670204, 96 2-(2-((2-ethyl-6-(1-(methylsulfonyl)...)
Affinity DataIC50: 126nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192922(US9670204, 136 2-((2-ethyl-6-(1-(methylsulfonyl)pi...)
Affinity DataIC50: 138nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM191789(US9670204, 32 2-(4-(2-ethyl-3-((4-(4-fluorophenyl)...)
Affinity DataIC50: 231nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192476(US9670204, 110 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 246nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192615(US9670204, 114 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 261nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM191794(US9670204, 36 ethyl2-(4-(2-ethyl-3-((4-(4-fluoroph...)
Affinity DataIC50: 280nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192190(US9670204, 87 N-(6-(1-(3-(dimethylamino)propyl-sul...)
Affinity DataIC50: 357nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192615(US9670204, 114 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 476nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192475(US9670204, 109 ethyl2-(4-(2-ethyl-3-((4-(4-fluorop...)
Affinity DataIC50: 480nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257779(CHEMBL4083879)
Affinity DataIC50: 493nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192286(US9670204, 98 N-(2-ethyl-6-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 533nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192172(US9670204, 80 N-(2-ethyl-6-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 710nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193117(US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...)
Affinity DataIC50: 771nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257798(CHEMBL4080051)
Affinity DataIC50: 804nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192187(US9670204, 84 N-(2-ethyl-6-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192172(US9670204, 80 N-(2-ethyl-6-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257812(CHEMBL4096556)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192923(US9670204, 137 2-((2-ethyl-6-(1-(methylsulfonyl)pi...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM191806(US9670204, 40 N-(2-ethyl-6-(4-oxazol-2-ylmethyl)pi...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193179(US9670204, 194 N-cyclopropyl-2-(4-(2-ethyl-3-((4-(...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257777(CHEMBL4070910)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192177(US9670204, 82 N-(2-ethyl-6-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM191807(US9670204, 41 N-(6-(4-((1,2,4-oxadiazol-3-yl)methy...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192186(US9670204, 83 4-(3,4-difluorophenyl)-N-(2-ethyl-6-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257814(CHEMBL4101875)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192291(US9670204, 100 4-(2,4-difluorophenyl)-N-(2-ethyl-6...)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192297(US9670204, 103 4-(4-fluorophenyl)-N-(2-ethyl-6-(1-...)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193000(US9670204, 180 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192790(US9670204, 125 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193363(US9670204, 226 N-(6-(4-((1H-imidazol-2-yl)methyl)p...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193117(US9670204, 192 N-(6-(4-((1H-imidazol-5-yl)methyl)p...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257815(CHEMBL4080946)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Galapagos

Curated by ChEMBL
LigandPNGBDBM193000(US9670204, 180 2-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 6.08E+3nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257807(CHEMBL4073638)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257776(CHEMBL4084005)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM192173(US9670204, 81 4-(4-tert-butylphenyl)-N-(2-ethyl-6-...)
Affinity DataIC50: 7.61E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
TargetAutotaxin(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM191808(US9670204, 42 2-(4-(2-ethyl-3-((4-(4-fluorophenyl)...)
Affinity DataIC50: 9.16E+3nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2019
Entry Details Article
PubMed
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