Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50002290
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM47353(US9687494, 25 | BDBM143220 | US9029362, 173)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456671(CHEMBL4215348)
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456669(CHEMBL4203158)
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456680(CHEMBL4208354)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456670(CHEMBL4210406)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456669(CHEMBL4203158)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456675(CHEMBL4212743)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456672(CHEMBL4211862)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456670(CHEMBL4210406)
Affinity DataKi:  2.70nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456677(CHEMBL4214810)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456671(CHEMBL4215348)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456678(CHEMBL4205452)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456673(CHEMBL4213285)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456680(CHEMBL4208354)
Affinity DataKi:  5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456676(CHEMBL4217172)
Affinity DataKi:  10nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456668(CHEMBL4204959)
Affinity DataKi:  15nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456679(CHEMBL4206975)
Affinity DataKi:  20nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456674(CHEMBL4217695)
Affinity DataKi:  31nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456667(CHEMBL4206562)
Affinity DataKi:  105nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456681(CHEMBL4209831)
Affinity DataKi:  209nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed