Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50001169
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271046BDBM50271046(CHEMBL4127005)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271056BDBM50271056(CHEMBL4127111)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271044BDBM50271044(CHEMBL4125726)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271058BDBM50271058(CHEMBL4128346)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271043BDBM50271043(CHEMBL4128703)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKLR(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271046BDBM50271046(CHEMBL4127005)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271057BDBM50271057(CHEMBL4128501)
Affinity DataIC50: 4.23E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271052BDBM50271052(CHEMBL4128970)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271060BDBM50271060(CHEMBL4129340)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271092BDBM50271092(CHEMBL4126536)
Affinity DataIC50: 5.08E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271095BDBM50271095(CHEMBL4128010)
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271048BDBM50271048(CHEMBL4126776)
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271046BDBM50271046(CHEMBL4127005)
Affinity DataIC50: 6.26E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM1 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271053BDBM50271053(CHEMBL4129306)
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKLR(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271043BDBM50271043(CHEMBL4128703)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271073BDBM50271073(CHEMBL4126021)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271054BDBM50271054(CHEMBL4127909)
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033731BDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 8.82E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271079BDBM50271079(CHEMBL4125882)
Affinity DataIC50: 9.98E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271047BDBM50271047(CHEMBL4130043)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033731BDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM1 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271050BDBM50271050(CHEMBL4130187)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271094BDBM50271094(CHEMBL4127315)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271049BDBM50271049(CHEMBL4128827)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271055BDBM50271055(CHEMBL4130279)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271043BDBM50271043(CHEMBL4128703)
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM1 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271042BDBM50271042(CHEMBL4126628)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271085BDBM50271085(CHEMBL4129013)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271090BDBM50271090(CHEMBL4126950)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271091BDBM50271091(CHEMBL4127929)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271041BDBM50271041(CHEMBL4127769)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271059BDBM50271059(CHEMBL4129726)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271093BDBM50271093(CHEMBL4129165)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271080BDBM50271080(CHEMBL4127266)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271045BDBM50271045(CHEMBL4130222)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271051BDBM50271051(CHEMBL4127576)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271081BDBM50271081(CHEMBL4128900)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50271084BDBM50271084(CHEMBL4127501)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKM2 expressed in Escherichia coli BL21 preincubated for 15 mins followed by PEP/NADH addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKLR(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033731BDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PKL expressed in Escherichia coli preincubated for 15 mins followed by PEP/NADH addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2020
Entry Details Article
PubMed