Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 50000066
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239957(CHEMBL4089861)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239961(CHEMBL4062836)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239956(CHEMBL4061792)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen after 24 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen after 24 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen after 24 hrs by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239959(CHEMBL4069824)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 17nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239953(CHEMBL4081049)
Affinity DataIC50: 18nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239955(CHEMBL4060150)
Affinity DataIC50: 159nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: 257nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239960(CHEMBL4090820)
Affinity DataIC50: 356nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 467nMAssay Description:Inhibition of recombinant human MMP12 expressed in baculovirus expression system using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 600nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 730nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human MMP12 expressed in baculovirus expression system using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50361639(CHEMBL1371684)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239953(CHEMBL4081049)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239953(CHEMBL4081049)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human MMP3 expressed in baculovirus expression system using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239955(CHEMBL4060150)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239955(CHEMBL4060150)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239955(CHEMBL4060150)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239954(CHEMBL4080520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239955(CHEMBL4060150)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239950(CHEMBL4088383)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239955(CHEMBL4060150)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239949(CHEMBL4098541)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239958(CHEMBL4105299)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Scripps Florida

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
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