Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50001053
TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50268404(CHEMBL4085881)
Affinity DataIC50: 26nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50268405(CHEMBL4068075)
Affinity DataIC50: 35nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50268406(CHEMBL4084009)
Affinity DataIC50: 45nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50268403(CHEMBL4064342)
Affinity DataIC50: 50nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
P.D. Patel Institute of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 101nMAssay Description:Inhibition of bovine liver DHFR pre-incubated 2 mins before dihydrofolic acid substrate addition and measured over 10 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed