Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50001051
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268397(CHEMBL4067852)
Affinity DataEC50:  1.67E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268398(CHEMBL4061940)
Affinity DataEC50:  1.67E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268399(CHEMBL4094467)
Affinity DataEC50:  2.78E+3nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268400(CHEMBL4081189)
Affinity DataEC50:  8.33E+3nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268401(CHEMBL4105584)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50142901(CHEMBL3758288)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of PXR in human hepatocytes assessed as induction of CYP450 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268397(CHEMBL4067852)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50268397(CHEMBL4067852)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2020
Entry Details Article
PubMed