Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50001044
TargetLeucine--tRNA ligase, cytoplasmic(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50268308(CHEMBL4061292)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of LRS-dependent mTORC1 activation in HEK293 cells assessed as reduction in leucine-induced mTORC1-mediated S6 Kinase phosphorylation pret...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase, cytoplasmic(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50268307(CHEMBL4074495)
Affinity DataIC50: 4.49E+4nMAssay Description:Inhibition of LRS-dependent mTORC1 activation in HEK293 cells assessed as reduction in leucine-induced mTORC1-mediated S6 Kinase phosphorylation pret...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase, cytoplasmic(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50268307(CHEMBL4074495)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of LRS canonical enzyme activity in HEK293 cells assessed as effect on enzyme-mediated aminoleucylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetLeucine--tRNA ligase, cytoplasmic(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50268308(CHEMBL4061292)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of LRS canonical enzyme activity in HEK293 cells assessed as effect on enzyme-mediated aminoleucylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed