Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50000981
LigandPNGBDBM50266936(CHEMBL4078601)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50266937(CHEMBL4095125)
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266938(CHEMBL4086456)
Affinity DataIC50: 316nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266952(CHEMBL4095509)
Affinity DataIC50: 501nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50266943(CHEMBL4102883)
Affinity DataIC50: 631nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266950(CHEMBL4081848)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266941(CHEMBL4105287)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266944(CHEMBL4071778)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM92725(Phenylboronic acid, 18)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26138((2-methoxyphenyl)boranediol | Phenylboronic Acid, ...)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266940(CHEMBL4087433)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26133(CHEMBL21427 | (4-methoxyphenyl)boranediol | Phenyl...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266955(CHEMBL4084348)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26131(4-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26996(Phenylboronic acid, 22 | benzeneboronic acid | CHE...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266954(CHEMBL3218996)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50391826(CHEMBL2146990)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266946(CHEMBL4082284)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266951(CHEMBL349516 | 3-(Hydroxymethyl)Benzene Boronic Ac...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50067906((3-aminophenyl)boronic acid, 1 | 3-aminophenyl bor...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26127((3-methoxyphenyl)boranediol | Phenylboronic Acid, ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26125(3-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266948(CHEMBL4060380)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266953(CHEMBL4079823)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM105193(4‐(1H‐imidazol‐1‐yl)phenol...)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266956(CHEMBL66861 | 4-Methanesulfonyl-Phenol)
Affinity DataIC50: 6.31E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266945(CHEMBL1229732)
Affinity DataIC50: 7.94E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50266949(CHEMBL4069065)
Affinity DataIC50: 1.26E+6nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed