Report error Found 171 Enz. Inhib. hit(s) with all data for entry = 50008580
Affinity DataEC50: 6nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 3.21E+3nMAssay Description:Inhibition of ALK L1152R mutant in human DFCI076 cells assessed as reduction in cell viability after 72 hrs by MTS assay in presence of osimertinibMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 84nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MT...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 96nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 666nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.66E+3nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 2.36E+3nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MT...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MT...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MT...More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MT...More data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Inhibition of EGFR T790M exon19 deletion double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 2.18E+3nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: >5.00E+3nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 961nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 39nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 8nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 1.75E+3nMAssay Description:Inhibition of EML4/ALK (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 827nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 988nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 93nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 989nMAssay Description:Inhibition of wild type EGFR (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 183nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 830nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by...More data for this Ligand-Target Pair
Affinity DataEC50: 78nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 195nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MT...More data for this Ligand-Target Pair
