Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50001009
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50178769(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267646(CHEMBL4102380)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267646(CHEMBL4102380)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267628(CHEMBL4074207)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50178769(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267662(CHEMBL4059756)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267628(CHEMBL4074207)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 4.71E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267654(CHEMBL4104634)
Affinity DataIC50: 4.94E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267627(CHEMBL4090805)
Affinity DataIC50: 5.11E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267662(CHEMBL4059756)
Affinity DataIC50: 5.48E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 8.25E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 9.81E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267648(CHEMBL4084417)
Affinity DataIC50: 9.98E+4nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267627(CHEMBL4090805)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267654(CHEMBL4104634)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267653(CHEMBL4092171)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267653(CHEMBL4092171)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267661(CHEMBL608379)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267646(CHEMBL4102380)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-3 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-3 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267648(CHEMBL4084417)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-1 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
H�Pital Kirchberg

Curated by ChEMBL
LigandPNGBDBM50267661(CHEMBL608379)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed