Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50035707
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM21130(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
Affinity DataKd:  4.30nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019093(CHEMBL291649 | 1-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKd:  8nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019094(CHEMBL60294 | 1-Allyl-3-(3-hydroxy-phenyl)-piperid...)
Affinity DataKd:  26nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019092(CHEMBL59989 | 3-(3-Hydroxy-phenyl)-1-methyl-piperi...)
Affinity DataKd:  36nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019093(CHEMBL291649 | 1-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKd:  120nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019097(CHEMBL293655 | 1-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKd:  154nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019091(CHEMBL300986 | 3-(3-Hydroxy-phenyl)-2-methyl-1-phe...)
Affinity DataKd:  170nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019098(CHEMBL303278 | 3-(3-Hydroxy-phenyl)-1,2-dimethyl-p...)
Affinity DataKd:  178nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019093(CHEMBL291649 | 1-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKd:  260nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019095(CHEMBL300357 | 1-Allyl-3-(3-hydroxy-phenyl)-2-meth...)
Affinity DataKd:  310nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019091(CHEMBL300986 | 3-(3-Hydroxy-phenyl)-2-methyl-1-phe...)
Affinity DataKd:  380nMAssay Description:Binding affinity at Opioid receptor mu 1 in rat brain membrane was determined by using curve-fitting ligands ([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019094(CHEMBL60294 | 1-Allyl-3-(3-hydroxy-phenyl)-piperid...)
Affinity DataKd:  450nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019097(CHEMBL293655 | 1-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKd:  625nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019094(CHEMBL60294 | 1-Allyl-3-(3-hydroxy-phenyl)-piperid...)
Affinity DataKd:  715nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019095(CHEMBL300357 | 1-Allyl-3-(3-hydroxy-phenyl)-2-meth...)
Affinity DataKd:  770nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019095(CHEMBL300357 | 1-Allyl-3-(3-hydroxy-phenyl)-2-meth...)
Affinity DataKd:  830nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019097(CHEMBL293655 | 1-Cyclopropylmethyl-3-(3-hydroxy-ph...)
Affinity DataKd:  830nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019098(CHEMBL303278 | 3-(3-Hydroxy-phenyl)-1,2-dimethyl-p...)
Affinity DataKd:  910nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019098(CHEMBL303278 | 3-(3-Hydroxy-phenyl)-1,2-dimethyl-p...)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019092(CHEMBL59989 | 3-(3-Hydroxy-phenyl)-1-methyl-piperi...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019091(CHEMBL300986 | 3-(3-Hydroxy-phenyl)-2-methyl-1-phe...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity at Opioid receptor kappa 1 in guinea pig brain membrane determined by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50019092(CHEMBL59989 | 3-(3-Hydroxy-phenyl)-1-methyl-piperi...)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity at Opioid receptor delta 1 in rat brain membrane was determined by using curve -fitting LIGAND([3H]DHM, [3H]DADL, [3H]DSLET, [3H]EKC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed