Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50000173
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241987(CHEMBL446997)
Affinity DataKd:  2.45E+4nMAssay Description:Binding affinity to human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241982(CHEMBL4093201)
Affinity DataKd:  7.30E+6nMAssay Description:Binding affinity to human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241991(CHEMBL4085438)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Electric eel AChE using acetylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241982(CHEMBL4093201)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to human AChE using acetylthiocholine as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50027343(CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50292572(CHEMBL15910 | 3,3-dimethylbutan-2-yl methylphospho...)
Affinity DataKd:  400nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50240416(diethyl 4-nitrophenyl phosphate | paraoxon | O,O-d...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241989(CHEMBL2179375)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 30 min followed by substrate addition measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241979(CHEMBL4066365)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of horse BChE using butyrylthiocholine iodide as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241979(CHEMBL4066365)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241988(CHEMBL592433)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 30 min followed by substrate addition measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241981(CHEMBL4072457)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241981(CHEMBL4072457)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241979(CHEMBL4066365)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241978(CHEMBL4093928)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241978(CHEMBL4093928)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of horse BChE using butyrylthiocholine iodide as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241980(CHEMBL4097266)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241978(CHEMBL4093928)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of Electric eel AChE using acetylthiocholine iodide as substrate measured for 30 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241980(CHEMBL4097266)
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241979(CHEMBL4066365)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of equine BChE assessed as equilibrium constant using butyrylthiocholine iodide as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Missouri St. Louis

Curated by ChEMBL
LigandPNGBDBM50241979(CHEMBL4066365)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human AChE assessed as equilibrium constant using acetylthiocholine as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed