Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50000089
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50437046(CHEMBL2403356)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Mouse)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at estrogen receptor in mouse GT1-7 cells harboring beta-galactosidase reporter gene assessed as reduction in 17beta-estradiol in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240314(CHEMBL4059760)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240313(CHEMBL4103516)
Affinity DataIC50: 134nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240312(CHEMBL4075785)
Affinity DataIC50: 154nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240310(CHEMBL4080172)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240309(CHEMBL4098201)
Affinity DataIC50: 225nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240308(CHEMBL4079256)
Affinity DataIC50: 271nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
National Institute of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50240311(CHEMBL4088044)
Affinity DataIC50: 664nMAssay Description:Antagonist activity at CMX-GAL4N fused human ERalpha expressed in HEK293 cells assessed as reduction in E2 induced response by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2019
Entry Details Article
PubMed