Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50003218
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468239(CHEMBL4284071)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468242(CHEMBL4288080)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468241(CHEMBL4280174)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468232(CHEMBL4292351)
Affinity DataIC50: 17nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468238(CHEMBL4278226)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468236(CHEMBL4276744)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468237(CHEMBL4284684)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468243(CHEMBL4291935)
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468233(CHEMBL4291900)
Affinity DataIC50: 95nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468235(CHEMBL4288482)
Affinity DataIC50: 97nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468234(CHEMBL4281283)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468240(CHEMBL4277822)
Affinity DataIC50: 101nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468237(CHEMBL4284684)
Affinity DataIC50: 143nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468239(CHEMBL4284071)
Affinity DataIC50: 449nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468242(CHEMBL4288080)
Affinity DataIC50: 491nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468232(CHEMBL4292351)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468243(CHEMBL4291935)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM149404(US8975249, I-4 | CO-1686 | Rociletinib | AVL-301 |...)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468235(CHEMBL4288482)
Affinity DataIC50: 500nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468238(CHEMBL4278226)
Affinity DataIC50: 592nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468236(CHEMBL4276744)
Affinity DataIC50: 767nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468241(CHEMBL4280174)
Affinity DataIC50: 800nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 823nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EGFR L858R/T790M mutant (695 to end amino acids) expressed in baculovirus infected Sf9 insect c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468233(CHEMBL4291900)
Affinity DataIC50: 961nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468240(CHEMBL4277822)
Affinity DataIC50: 996nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50468234(CHEMBL4281283)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type N-terminal GST tagged human recombinant EGFR (695 to end amino acids) expressed in baculovirus infected Sf9 insect cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed