Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50000168
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241906(CHEMBL4069853)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241905(CHEMBL4080164)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM50241901(CHEMBL4065026)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full length HDAC1 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 2(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 740nMAssay Description:Inhibition of recombinant human full length HDAC2 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM25150(Belinostat | (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC6 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC4 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University (Tmu)

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC8 using Fluor-de-Lys as substrate after 60 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed